Interactive Learning Module
RCEM-aligned ED Teaching

Acute Abdominal Emergencies

Acute abdominal pain approach · BIOPI Framework · GI Bleed · Bowel Obstruction · Appendicitis · Pancreatitis · Cholecystitis · AAA · Sepsis & Shock

Dr Igwe Joshua · FRCEM 11 Sections RCEM & NICE Aligned Interactive Module
Overview

Learning Objectives

By the end of this module you should be able to:
  • Understand the epidemiology of abdominal pain in the UK ED
  • Apply a structured, senior-level approach to the acute abdomen
  • Classify pain by type (visceral, somatic, referred) and by anatomical region
  • Recognise the five BIOPI categories of surgical emergency
  • Identify never-miss diagnoses and dangerous diagnostic mimics
  • Apply condition-specific management aligned to RCEM, NICE, and NHS England pathways
  • Manage special populations: elderly, pregnant, immunocompromised
  • Dispose patients safely and document to medico-legal standard

Guidance referenced RCEM

Section 1

Epidemiology

Who is the Patient? What Is the Risk?

5–10% of all UK ED presentations involve abdominal pain
  • 14–40% ultimately require surgical intervention
  • Most common final diagnosis: non-specific abdominal pain (NSAP) — 41–46%
  • Misdiagnosis in elderly carries significantly higher mortality. Exact figures vary by source.
Approximate cause frequency (Brewer et al.; US dataset)
  • NSAP 41–46%  |  Appendicitis 4–24%  |  Cholecystitis 2.5–9%
  • Gastroenteritis 7%  |  UTI 3–5%  |  SBO 2.5–4%  |  Renal colic 1.5–4%
  • Pancreatitis 1–2%  |  Diverticulitis 1–2%  |  AAA / Ectopic <1%
Clinical challenge
  • 1 in 3 patients present atypically — this is the default, not the exception
  • Scope includes surgical, vascular, gynaecological, retroperitoneal, and medical causes
Elderly (>65)
  • Attenuated pain response, absent fever in sepsis, absent peritonism in perforation
  • 2× more likely to require surgery — lowest threshold for CT and admission
Women of childbearing age
  • Beta-hCG strongly recommended in every case — missed ectopic is a leading cause of maternal death (MBRRACE)
Immunocompromised
  • HIV, solid organ transplant, haematological malignancy, anti-TNF / rituximab therapy
  • Peritonism and fever may both be absent — rely on CT, not examination alone
Post-operative patients
  • Adhesions dominate — risk of SBO, anastomotic leak, abdominal collection
Pregnancy
  • Any trimester: pain anatomy distorted, USS / MRI preferred over CT in first trimester

Guidance referenced MBRRACE-UK

Section 2

Structured ED Assessment

The Acute Abdomen: Think Before You Scan

Definition: Sudden, severe abdominal pain requiring urgent ED evaluation
  • Mortality rises with delay — identify haemodynamic compromise first, history second
Immediate resuscitation priorities
  • ABCDE. Two large-bore IV cannulae. Bloods and IV fluids if shocked.
  • Permissive hypotension in suspected vascular catastrophe (target SBP 70–80 until surgical haemostasis)
Ask five diagnostic questions (Sarikaya framework)
  • WHO is this patient? (age, sex, PMH, medications, surgical history)
  • WHAT are the probable diagnoses?
  • WHY do you think that? (clinical reasoning)
  • HOW do you prove it? (investigations)
  • WHEN to call the surgeon?
SOCRATES
  • Site — location at onset and now
  • Onset — sudden (vascular) vs gradual (inflammatory)
  • Character — colicky, constant, burning, tearing
  • Radiation — back (AAA/pancreatitis), shoulder tip (diaphragmatic)
  • Associated symptoms — nausea, vomiting, fever, PR bleed
  • Timing — worse since onset = bad sign
  • Exacerbating / relieving factors
  • Severity — 0–10, change over time
Contextual history
  • PMH: prior episodes, DM, AF, vascular disease, IBD, malignancy
  • Surgical history: adhesions, hernias, stomas, prior aortic surgery
  • Medications: NSAIDs, anticoagulants, steroids, immunosuppressants
  • GYN/URO: LMP, PV bleeding/discharge, prior ectopic, IUD
  • Social: alcohol, IV drug use, home situation, recent travel
Key timing questions
  • Vomiting before or after pain? (SBO vs appendicitis vs Boerhaave)
  • Change in bowel habit? Last flatus?
General
  • Vital signs, GCS, perfusion, hydration
  • Patient position: writhing (colic) vs still (peritonitis)
Inspection
  • Distension, scars, hernial orifices (groin, umbilicus, incisions)
  • Cullen’s / Grey Turner’s sign (retroperitoneal bleed — late)
Palpation
  • Localise tenderness, masses, pulsatile AAA
  • Peritonism: guarding, rigidity, rebound
  • McBurney’s point, Murphy’s sign
  • Psoas sign (retroperitoneal irritation)
Auscultation
  • Tinkling (obstruction) vs silence (ileus/peritonitis)
Extra-abdominal exam — never omit
  • Chest: bases (basal pneumonia mimics acute abdomen)
  • Heart: new murmur, AF (SMA embolism risk)
  • Groin: femoral hernia (missed strangulation)
  • Genitalia / scrotal exam where indicated
Rectal examination
  • Perform when clinically indicated: PR bleeding, melaena, pelvic mass, prostatic pathology
Vaginal examination
  • Perform when clinically indicated and with consent: cervical excitation (PID/ectopic), adnexal mass, PV discharge
Section 3

Understanding Abdominal Pain

Visceral · Somatic · Referred

Visceral pain
  • Poorly localised, midline, cramping or aching — organ distension, ischaemia, spasm
  • Mediated via sympathetic fibres — bilges towards the corresponding spinal level
Somatic (parietal) pain
  • Well-localised, sharp, exacerbated by movement — parietal peritoneum irritation
  • Guarding and rigidity are somatic responses — serious sign
Referred pain
  • Diaphragmatic irritation → shoulder tip (C3–5)
  • Renal/ureteric pain → groin / anterior thigh
  • Biliary pain → right scapula (T6–8)
Spinal level reference
  • C3–5: liver, spleen, diaphragm  |  T5–9: stomach, gallbladder, pancreas
  • T8–T10: small bowel  |  T10–L1: colon, kidney  |  S2–4: bladder, rectum
RUQ
  • Cholecystitis / biliary colic, cholangitis, hepatitis / hepatic abscess, pancreatitis
  • Renal colic (right), peptic ulcer disease, right basal pneumonia, PE / inferior MI
LUQ
  • Gastritis / gastric ulcer, splenic pathology (rupture, infarct), pancreatitis (tail)
  • Renal colic (left), left basal pneumonia / PE
RLQ
  • Appendicitis, ovarian cyst / torsion, ectopic pregnancy, inguinal / femoral hernia
  • Renal colic, IBD (Crohn’s), AAA (right extension), caecal volvulus / tumour
LLQ
  • Diverticulitis, sigmoid volvulus / tumour, ovarian cyst / torsion, ectopic pregnancy
  • Inguinal hernia, IBD (UC), AAA (left extension)
Epigastric
  • Peptic ulcer / GORD, pancreatitis, perforated viscus, biliary disease
  • Inferior MI — up to 30% of cases (do ECG first)
  • Aortic dissection type A
Central / periumbilical
  • Early appendicitis (pre-migration), small bowel obstruction, mesenteric ischaemia
  • Aortic aneurysm, hernia (umbilical)
Suprapubic
  • UTI / urinary retention, ectopic / pelvic pathology, PID, ovarian cyst / torsion
Diffuse
  • Peritonitis (any cause — perforation, pancreatitis, ischaemia)
  • IBD — acute severe colitis / toxic megacolon
  • Mesenteric ischaemia (late), diabetic ketoacidosis (DKA) / metabolic, sickle cell crisis, adrenal crisis
Section 4

Investigations

Directed, Not Reflexive

Bloods (directed by presentation)
  • FBC, U&E, LFT, CRP, amylase/lipase, coagulation, G&S
  • Lactate: raised in ischaemia, sepsis, strangulation
  • Troponin: if cardiac differential in epigastric pain
  • Beta-hCG: recommended in all women of childbearing age
  • Cortisol: if adrenal crisis suspected
Urinalysis
  • Haematuria: renal colic, urothelial malignancy
  • Do not diagnose UTI as cause of abdominal pain without senior review
ECG
  • Mandatory in all epigastric and upper abdominal pain
  • Right-sided leads (V4R) if inferior MI suspected
Imaging
  • Erect CXR: free air (70–80% sensitivity for perforation)
  • AXR: limited utility — bowel obstruction, volvulus, calcified AAA
  • Bedside USS: AAA (first in any shock + abdominal pain >50)
  • Formal USS: gallstones, ovarian pathology, ectopic, hepatic
  • CT A/P with IV contrast: workhorse of abdominal emergency imaging
  • CT KUB (non-contrast): renal colic — 96% sensitivity
  • CT angiography: active GI bleeding, mesenteric ischaemia, EVAR
  • MRI: pregnancy (2nd/3rd trimester), biliary (MRCP), spinal cord compression
There are no standard belly labs
  • Directed approach only — investigations should answer a specific question
Section 5

The BIOPI Framework

Five Categories of Surgical Urgency

Five Major Categories of the Acute Abdomen

B

Bleeding or rupture of vessels or tumour

  • AAA, splenic rupture, ectopic pregnancy, hepatic haematoma, retroperitoneal haemorrhage
  • Hallmark: haemodynamic instability, anaemia. Bedside USS first. Activate MTP.
I

Ischaemia or Infarction

  • Mesenteric ischaemia, renal infarction, testicular torsion
  • Hallmark: pain out of proportion to examination. Lactate raised. CT angiography.
O

Obstruction

  • SBO, LBO, sigmoid/caecal volvulus, biliary obstruction, ureteric obstruction
  • Hallmark: distension, vomiting (early in SBO), absolute constipation. AXR + CT.
P

Perforation

  • Peptic ulcer, appendix, diverticular, Boerhaave syndrome
  • Hallmark: sudden onset, peritonism, free air on erect CXR. Urgent surgical referral.
I

Inflammation

  • Appendicitis, cholecystitis, pancreatitis, diverticulitis, IBD
  • Hallmark: fever, localised tenderness, raised WBC/CRP. CT for diagnosis.
Section 6

Things Never to Mix Up

Dangerous Mimics · Diagnostic Pitfalls

Dangerous Mimics: True Diagnosis vs Initial Misdiagnosis

True DiagnosisCommonly Misdiagnosed As
Ruptured AAARenal colic, lumbar strain, diverticulitis
Mesenteric ischaemiaGastroenteritis, constipation, ileus, SBO
Ectopic pregnancyPID, UTI, corpus luteum cyst, appendicitis
Inferior MIGORD, epigastric pain, pancreatitis
Aortic dissection type AEpigastric pain, MI, PE
Perforated viscusPUD, pancreatitis, non-specific abdominal pain
Strangulated herniaIleus, small bowel obstruction
Sigmoid/caecal volvulusConstipation, functional bloating
Adrenal crisisSepsis, shock of unknown cause
Appendicitis (elderly/pregnant)UTI, gastroenteritis, musculoskeletal
Never miss

AAA vs Renal Colic

  • Both present with flank / back pain radiating to groin — misdiagnosis kills
  • AAA: pulsatile mass, haemodynamic instability, collapse, known aneurysm on history
  • Renal colic: haematuria, writhing in agitation, colicky, prior episodes, younger age
  • Low threshold for bedside AAA ultrasound in all patients >50 with flank, back, or abdominal pain
  • Do not assume renal colic in a patient >60 without first excluding AAA
  • Patient with ‘renal colic’ who drops BP has an AAA until proved otherwise
  • Do NOT send a haemodynamically unstable patient to CT without a surgeon present
  • CT confirms AAA diagnosis but never delay surgery for CT in collapse
  • Permissive hypotension (SBP 70–80), MTP activation, immediate vascular referral
Never miss

Ectopic Pregnancy vs Appendicitis

  • Both: RIF pain, nausea, low-grade fever, raised WBC — clinically indistinguishable at first
  • Ectopic rupture causes haemorrhagic shock and death
  • RULE: Beta-hCG in every woman of childbearing age with abdominal pain — recommended in all cases.
  • Positive beta-hCG + pain + haemodynamic compromise = ruptured ectopic until proved otherwise
  • TVS ultrasound: intrauterine pregnancy, free fluid, adnexal mass, empty uterus
  • Appendicitis in pregnancy: pain shifts superiorly — USS first, MRI if inconclusive
  • MBRRACE UK 2023: missed ectopic remains a leading cause of direct maternal death
Never miss

Mesenteric Ischaemia vs Gastroenteritis

  • Classic teaching: pain out of proportion to examination — soft abdomen despite severe pain
  • Late disease: peritonism = dead bowel. High mortality if diagnosis delayed.
  • Risk profile: age >60, AF, vascular disease, recent aortic intervention, cardiac emboli
  • RULE: AF + acute abdominal pain = SMA embolism until proved otherwise
  • Do not diagnose gastroenteritis in a patient >60 with vascular risk factors without excluding mesenteric ischaemia
  • Lactate: raised but non-specific. CT angiography is diagnostic. Normal lactate does not exclude early mesenteric ischaemia.
  • ECG strongly recommended — identify AF as embolic source
  • Vascular and surgical emergency. Time is bowel.
Never miss

Inferior MI vs Epigastric / Upper GI Pain

  • Inferior MI presents as epigastric pain, nausea, vomiting in up to 30% of cases
  • Right ventricular MI: add right-sided leads (V4R) — ST elevation V4R is diagnostic
  • Aortic dissection type A also presents with epigastric / chest pain: wide mediastinum on CXR
  • RULE: ECG before attributing any epigastric or upper abdominal pain to a GI cause
  • Beware the patient who says ‘indigestion’ but looks pale, diaphoretic, and unwell
  • GTN, troponin, serial ECGs, cardiology involvement before any upper GI procedure
  • Avoid performing OGD or NG tube in undiagnosed MI
Never miss

Sigmoid / Caecal Volvulus vs Constipation

  • Sigmoid volvulus: elderly, institutionalised, psychiatric patients on constipating drugs
  • AXR: ‘coffee bean’ or ‘omega loop’ sign, apex pointing to RUQ
  • Caecal volvulus: younger patients, right-sided distension on AXR
  • Both are surgical emergencies — perforation and ischaemia follow delay
  • Do not discharge a distended patient with laxatives before obtaining imaging.
  • Sigmoid volvulus: flexible sigmoidoscopy / CT-guided decompression first-line if no peritonism
  • Caecal volvulus: surgery required in most cases — no endoscopic option
  • Involve colorectal surgery before committing to any management plan

Guidance referenced MBRRACE-UK

Section 7

Condition-Based Management

Key Diagnoses · RCEM & NICE Aligned

Clinical features
  • Central pain migrating to RIF (McBurney’s point)
  • Anorexia, nausea, low-grade pyrexia
  • Rovsing’s sign, psoas sign, Dunphy’s sign
  • Atypical in elderly, pregnant, immunocompromised
  • Alvarado score for risk stratification
  • RIF tenderness is the most consistent clinical feature
  • Fever is unreliable as a diagnostic feature
ED Management (NICE CKS Appendicitis)
  • CT abdomen/pelvis if diagnosis unclear after clinical assessment
  • USS first line in children and pregnant women
  • NBM, IV fluids, analgesia — do not withhold opioids
  • Early surgical referral for Alvarado ≥7
  • NICE supports conservative antibiotics in uncomplicated cases
  • Admit all with peritonism for operative planning
  • Perforation risk increases significantly with delayed diagnosis
Small Bowel Obstruction (SBO)
  • Causes: adhesions (65%), hernia, tumour, Crohn’s, gallstone ileus
  • Colicky central pain, vomiting early, absolute constipation late
  • AXR: central loops >3 cm, ‘stack of coins’ valvulae conniventes
  • CT confirms cause, identifies strangulation, closed-loop obstruction
Strangulation = emergency surgery
  • Fever + peritonism + raised lactate = ischaemia until proved otherwise
Management
  • NG tube (free drainage), IV fluids, catheter, NBM
  • Early surgical referral — urgent surgery if strangulation suspected
Large Bowel Obstruction (LBO)
  • Causes: colorectal cancer 60%, sigmoid volvulus 20%, diverticular
  • Distension dominant, vomiting late, absolute constipation
  • AXR: peripheral large bowel >6 cm, caecum >9 cm = impending rupture
Causes
  • Perforated peptic ulcer (most common surgical GI emergency)
  • Perforated diverticular, appendix, tumour, Boerhaave syndrome
Presentation
  • Sudden onset severe pain, rapid generalisation to peritonism
  • Rigid ‘board-like’ abdomen — haemodynamic instability = sepsis with peritonitis
Management (NELA/RCS guidelines)
  • Resuscitate: IV fluids, IV antibiotics as per local Trust antimicrobial guideline
  • NG tube, urinary catheter, NBM, VTE prophylaxis when safe
  • Urgent surgical referral — time-critical diagnosis
Diagnosis (NICE NG104)
  • Epigastric pain radiating to back, nausea, vomiting, low-grade fever
  • Amylase or lipase >3× upper limit of normal
  • Causes: gallstones 45%, alcohol 35%, idiopathic, hypercalcaemia, drugs
Management
  • IV fluids: aggressive early resuscitation — Hartmann’s preferred (NICE)
  • Analgesia: IV opioids first-line, consider PCA
  • Encourage oral intake as tolerated
  • Do not give prophylactic antibiotics (NICE NG104)
  • ERCP within 24–48h if gallstone pancreatitis + cholangitis
Biliary colic
  • Episodic RUQ/epigastric pain after fatty meals, no fever, USS: gallstones
  • Discharge with analgesia (diclofenac 75 mg IM), elective surgical referral
Acute cholecystitis (Tokyo Guidelines)
  • Murphy’s sign positive, fever, raised WBC/CRP, persistent RUQ pain >6h
  • IV antibiotics, IV fluids, surgical referral
  • Early laparoscopic cholecystectomy within 1 week (NICE CG188)
Ascending cholangitis — LIFE-THREATENING
  • Charcot’s Triad: fever + RUQ pain + jaundice
  • Reynolds’ Pentad adds confusion + hypotension = septic shock
  • Blood cultures, broad-spectrum IV antibiotics, IV fluids, urgent ERCP
  • RULE: Ascending cholangitis = life-threatening emergency. Do not discharge.
Risk stratification (NICE CG141)
  • Glasgow-Blatchford score (GBS): BUN, Hb, SBP, HR, syncope, melaena
  • Pre-endoscopy GBS 0 = offer early discharge with outpatient endoscopy
  • HR >100 + SBP <100 = haemodynamically significant bleed
ED Management
  • 2 large-bore IV cannulae, FBC, clotting, crossmatch 4 units
  • Restrictive transfusion: Hb <70 g/L (or <80 if active cardiac disease)
  • Terlipressin 2 mg IV if variceal bleeding suspected
  • Offer endoscopy immediately if haemodynamically unstable, within 24h for all others
Causes
  • Diverticular disease (most common), angiodysplasia, colorectal cancer, ischaemic colitis, IBD
Key pitfalls
  • Avoid attributing PR bleeding to haemorrhoids without excluding colorectal malignancy
  • 15% of apparent LGIB is upper GI bleeding — OGD first if source not excluded
  • CT angiography for active bleeding localises source for embolisation
Classification
  • Irreducible: cannot reduce — contents trapped
  • Incarcerated: contents obstructed — emergency
  • Strangulated: vascular compromise + ischaemia = surgical emergency
ED decision making
  • Tense, tender, erythematous hernia + systemic features = strangulated
  • RULE: Do NOT attempt manual reduction of a strangulated hernia
  • Femoral hernia: highest strangulation risk — frequently missed
Ectopic Pregnancy
  • Positive beta-hCG + pain → transvaginal USS immediately
  • Haemodynamic compromise = emergency surgical management
  • Anti-D immunoglobulin if Rh-negative
Ovarian Torsion
  • Sudden onset severe unilateral lower abdominal pain
  • Normal Doppler does NOT exclude torsion
  • Gynaecology review urgently — time = ovary
PID
  • Bilateral pelvic pain, PV discharge, cervical excitation, fever
  • BASHH guidelines: IM ceftriaxone + oral doxycycline + metronidazole 14 days
HELLP Syndrome
  • RUQ pain + raised LFT + thrombocytopenia + hypertension
  • Variant of severe pre-eclampsia — emergency obstetric involvement
Acute severe UC
  • Truelove and Witts: >6 bloody stools/day + systemic upset
  • IV hydrocortisone 100 mg QDS. CT to exclude perforation.
  • Involve gastroenterology and colorectal surgery from day one
Toxic megacolon
  • Transverse colon >6 cm on AXR + systemic toxicity
  • Avoid antispasmodics and opioids — worsen distension
  • Emergency surgical consultation — high mortality with delay
Abdominal Trauma
  • Primary survey first (ATLS). Spleen: most commonly injured solid organ.
  • Positive FAST + unstable = emergency laparotomy without CT

Guidance referenced NICE NG104 · NICE CG188 · BSG · BASHH · Tokyo Guidelines · NELA · RCS · ATLS

Section 8

Retroperitoneal Emergencies

High Mortality · Easily Missed · CT is Diagnostic

Key retroperitoneal structures
  • Aorta / IVC, kidneys and ureters, adrenal glands
  • Pancreas (body/tail), duodenum (2nd–4th parts)
  • Ascending and descending colon, sympathetic chains
Clinical significance
  • Retroperitoneal bleeding does NOT irritate peritoneum
  • Examination frequently normal even in massive haemorrhage
  • CT is definitive — bedside USS limited in retroperitoneum
Ruptured AAA
  • Classic triad (pain + collapse + pulsatile mass) present in <50%
  • Permissive hypotension: target SBP 70–80 until haemostasis
  • Crossmatch 10 units RBC + FFP. Activate MTP.
  • Immediate vascular surgery referral and theatre activation
Retroperitoneal haematoma
  • Causes: pelvic fracture (most common traumatic), aortic rupture, anticoagulants
  • Femoral neuropathy: groin + anterior thigh pain, hip flexion weakness
Renal Emergencies
  • Renal colic: CT KUB 96% sensitivity. NSAIDs first-line (diclofenac 75 mg IM).
  • Admit if: stone >10 mm, single kidney, infection, bilateral obstruction
Urosepsis with obstruction
  • Infected hydronephrosis = urological emergency — high mortality without drainage
  • Broad-spectrum IV antibiotics immediately + urology for nephrostomy within hours
Adrenal crisis (Addisonian)
  • Hypotension + hyponatraemia + hyperkalaemia + hypoglycaemia
  • Do NOT wait for cortisol result: hydrocortisone 100 mg IV immediately
Phaeochromocytoma crisis
  • Paroxysmal hypertension, headache, diaphoresis, palpitations
  • Do NOT give beta-blockers without prior alpha-blockade
Psoas abscess
  • Back/flank pain, fever, hip flexion deformity (psoas sign)
  • CT-guided or surgical drainage + IV antibiotics. Consider TB.
Necrotising fasciitis (Fournier’s gangrene)
  • Perineal NF extending retroperitoneally — crepitus, gas on imaging
  • Mortality >30%. Surgical debridement within 6h.
Section 9

Special Populations

Elderly · Pregnant · Immunocompromised

Why the elderly are different
  • Attenuated pain response: minimal pain despite perforation, ischaemia, or obstruction
  • Peritonism and fever frequently absent even in septic peritonitis
  • Polypharmacy: NSAIDs mask pain, anticoagulants increase bleeding, steroids mask signs
High-risk diagnoses
  • AAA: first consideration in any >65 with back, flank, or abdominal pain
  • Mesenteric ischaemia: AF, post-MI, vascular disease — time is bowel
  • Cholecystitis: higher complication rate — empyema, perforation
  • Sigmoid volvulus: institutionalised, laxative-dependent patients
ED approach
  • Lower threshold for CT. Discuss with seniors early. Err on the side of admission.
  • Social history is clinical: who is at home, falls risk, baseline cognition
Establish gestational age and LMP before investigation
Differential by trimester
  • First: ectopic pregnancy, miscarriage, corpus luteum cyst, UTI
  • Second/third: placental abruption, preterm labour, HELLP syndrome, appendicitis
  • Any trimester: ovarian torsion, biliary disease, appendicitis, PE
HELLP Syndrome (obstetric emergency)
  • Haemolysis + Elevated LFTs + Low Platelets + hypertension
  • Emergency obstetric involvement immediately
Non-negotiable
  • Call obstetrics early. Your role is stabilisation and recognition.
  • Anti-D immunoglobulin if Rh-negative in any bleeding or abdominal trauma
Who is immunocompromised in the ED?
  • HIV/AIDS, solid organ transplant, haematological malignancy, active chemotherapy
  • Long-term steroids, anti-TNF, rituximab, JAK inhibitors
Why presentations differ
  • Fever may be absent even in severe sepsis
  • Peritonism minimal or absent — examination cannot be relied upon
Key diagnoses
  • Neutropenic enterocolitis (typhlitis): right-sided pain + fever + diarrhoea
  • CMV colitis: bloody diarrhoea in HIV
Approach
  • Broad-spectrum IV antibiotics promptly if sepsis suspected
  • CT is strongly recommended — do not rely on examination alone
  • Involve haematology / oncology / infectious diseases early

Guidance referenced NICE NG253

Section 10

ED Management & Disposition

Algorithms · Decision Points · Safety

Step 1: Immediate
  • ABCDE — identify haemodynamic instability before detailed history
  • Two IV cannulae, venous bloods, bedside USS in shock, ECG in epigastric pain
  • IV access + analgesia (do not withhold opioids) + antiemetics
Step 2: Investigations
  • Bloods: FBC, U&E, LFT, CRP, amylase/lipase, coagulation, lactate, G&S, beta-hCG
  • Imaging: directed by clinical assessment — USS, CT, erect CXR
Step 3: Diagnosis & risk stratification
  • Apply BIOPI framework: which category? Surgical urgency?
  • Red flag present? Peritonism, haemodynamic instability, raised lactate
Step 4: Escalation
  • Involve surgery, vascular, gynaecology, urology based on diagnosis
  • Senior review if uncertain — serial examination and vital signs
Emergency theatre — do not delay
  • Haemodynamically unstable: ruptured AAA, ruptured ectopic, dead bowel
  • Positive FAST + instability, peritonitis with deterioration
Admission: ward / surgical assessment
  • Peritonism, obstruction, pancreatitis, perforated viscus, ascending cholangitis
  • Any diagnosis requiring IV antibiotics, fluids, or further investigation
  • Uncertain diagnosis in high-risk patient (elderly, immunocompromised, pregnant)
Observation / short-stay
  • Serial examination and serial bloods for evolving diagnosis
  • Alvarado 4–6, mild pancreatitis stabilising, LGIB that has stopped
Discharge home with abdominal warnings
  • Biliary colic, uncomplicated UTI, constipation — only after senior review
  • Clear return instructions: specific symptoms, time window, route of return
  • Document understanding and agreed return criteria
Section 11

Documentation & Safety Netting

Protect Your Patient. Protect Your Practice.

Every ED abdominal pain note must include
  • Documented clinical reasoning: why you reached your working diagnosis
  • Relevant negatives: what you considered and excluded
  • Investigations: results reviewed, acted upon, and timeframe documented
  • Reassessment: time of re-examination and clinical status
  • Escalation: who you spoke to, at what time, and what was agreed
  • Disposition: explicit rationale for discharge or admission
Safety netting — document explicitly
  • What the patient was told to look out for (specify symptoms)
  • Patient understood and was able to act on the advice
  • Return pathway: which department, by when, under what circumstances
Never write
  • ‘Pain not surgical’ without a documented examination and reasoning
  • ‘NAD’ without listing what was examined
  • ‘Discharged home well’ without documented safety netting
01

5–10% of ED attendances. Time-critical diagnoses kill when missed.

02

Vascular pathology first in every differential — AAA, mesenteric ischaemia, ectopic.

03

BIOPI framework: Bleeding, Ischaemia, Obstruction, Perforation, Inflammation.

04

1 in 3 present atypically — the presentation you expect is the minority.

05

ECG before attributing epigastric pain to any GI cause.

06

Beta-hCG in every woman of childbearing age — recommended in all cases.

07

Retroperitoneal bleeding is invisible on examination — CT is your diagnostic tool.

08

The elderly are different — attenuated signs, highest complication rate.

09

Document reasoning, negatives, safety net. Every encounter. Every time.

10

When in doubt: reassess, re-examine, escalate, and document the conversation.

Clinical Pearl

"The strongest clinicians know when to follow protocol and when to think beyond it."

Dr Joshua Igwe · FRCEM

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